HOCKEMEYER LAB

Studying Human Diseases using Genomics and Primary Cell Models

CURRENT MEMBERS

Principal Investigator

Dirk Hockemeyer

Associate Professor of Cell and Developmental Biology
Molecular and Cell Biology, UC Berkeley

Postdoctoral Fellow in Genetics (2007-2012)
Advisor: Dr. Rudolf Jaenisch, Whitehead Institute

Ph.D. in Molecular and Cell Biology (2002-2007)
Advisor: Dr. Titia de Lange, Rockefeller University

B.S. and M.S. in Biochemistry (1998-2002)
Advisor: Dr. Alfred Nordheim, Eberhard Karls University Tuebingen

Staff Research Associates

Stella Tran

B.S. in Biochemistry, Minor in Microbiology
California State University, Long Beach

Research interests in the lab: Studying the role of POT1 protein in telomere length regulation and also studying human diseases using functional genomics in primary stem cell models.

E-mail address: stellatran[at]berkeley.edu

Postdoctoral Fellows

Robert Lu

Ph.D. in Medicine (2016-2020)
Children's Medical Research Institute, University of Sydney, Australia

B.S. in Biochemistry (2011-2014)
University of Sydney, Australia

Research interests in the lab: I'm interested in using leveraging genetic stem cell models to study how telomere maintenance mechanisms become activated in cancers.

E-mail address: robertlu_dh[at]berkeley.edu

Graduate Students

Vincent Pham

Ph.D. Candidate in Molecular and Cell Biology
University of California, Berkeley

M.S. in Biology
Tufts University

B.S. in Neuroscience
Brown University

Research interests in the lab: I am studying the contribution of neural crest cells in the development of the heart and the gene regulatory networks that govern species-specific regenerative response to heart injury. I'm using hiPSC/hESC-derived cardiac organoids (cardioids) to study this in humans.

E-mail address: vincent.pham[at]berkeley.edu

Anna Horacek

Ph.D. Candidate in Molecular and Cell Biology
University of California, Berkeley

B.S. in Biology and Anthropology and Minor in Chemistry
University of Oregon

Research interests in the lab: Employing next-generation sequencing to study the role of disordered protein domains in DNA-protein interactions during stem cell development.

E-mail address: annahoracek[at]berkeley.edu

Jan Schabort

Ph.D. Candidate in Molecular and Cell Biology
University of California, Berkeley

M.S. in Veterinary Biochemistry (2019-2021)
Advisor: Dr. Je-Yoel Cho, Seoul National University

B.S. in Biochemistry (2014-2018)
Advisor: Dr. Michael Carastro

Research interests in the lab: My interest lies in leveraging our human pluripotent stem cell system and acute and high-throughput incorporation of genetic mutations to understand the regulation of the telomeric overhang and specifically how these processes are disrupted in diseases such as cancer or Coats Plus Syndrome.

E-mail address: j.schabort[at]berkeley.edu

Carter Simington

Ph.D. Candidate in Molecular and Cell Biology
University of California, Berkeley

M.S. in Biochemistry and Molecular Biology
Johns Hopkins Bloomberg School of Public Health

B.S. in Biochemistry, Molecular and Cellular Biology
University of Arizona

Research interests in the lab:Uncovering the molecular mechanism of telomere length homeostasis

E-mail address: carter_simington[at]berkeley.edu

Shayan Hosseinzadeh

Ph.D. Candidate in Molecular and Cell Biology
University of California, Berkeley

B.S. in Biochemistry (2010-2014)
Advisor: Dr. Herbert Waite, UCSB

Research interests in the lab: Sequence-function analysis of the shelterin protein, TRF2, and its protein interaction partners to study their essential functions for telomere protection and telomere length homeostasis in human pluripotent stem cells.

E-mail address: shayanrhoss[at]berkeley.edu

Shaghayegh Jahanbani

Ph.D. Student in Molecular and Cell Biology
University of California, Berkeley

E-mail address: sjahanbani[at]berkeley.edu

Lindsey Qian

Ph.D. Student in Molecular and Cell Biology
University of California, Berkeley

B.S. in Biology, specialization in Developmental Biology (2019-2023)
Advisor: Dr. Victoria Prince, University of Chicago

E-mail address: lqian[at]berkeley.edu

Xiaoying Xiao

Ph.D. Student in Molecular and Cell Biology
University of California, Berkeley

E-mail address: xiaoying[at]berkeley.edu

Undergraduate Researchers

Jianpu Gao

B.A. in Data Science and Statistics, College of Computing, Data Science, and Society
University of California, Berkeley

Research interests in the lab:Employing machine learning and ai-based algorithms for multi-linear regression training in genetic study and automation for image recognition and classification.

E-mail address:jianpugao[at]berkeley.edu

Richard Ho

B.A. in Molecular and Cell Biology, Molecular Therapeutics
University of California, Berkeley

Research interests in the lab:Functionally characterizing mutants in telomeric DNA-protein complexes using high-throughput immunofluorescent assays.

E-mail address:richardho[berkeley.edu

Maya Singh

Undergraduate Research Assistant in Molecular and Cell Biology
University of California, Berkeley

Research interests in the lab:Characterizing BRCA2 Loss of Function Mutants with Imaging-Based Methods

E-mail address:mayasingh[at]berkeley.edu

Frances Kueper

B.A. in Molecular and Cell Biology (2023-2027)
University of California, Berkeley

Research interests in the lab:Identifying tissue-specific genetic drivers of BRCA2-related cancers

E-mail address:frances_k[at]berkeley.edu