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Hockemeyer Lab – Studying Human Diseases using Genomics and Primary Cell Models

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Welcome To The Hockemeyer Lab

The focus of our work is to establish reliable models of human diseases using genetically engineered human and stem cell and mouse models and functional genomics screening approaches. We are particularly interested in developing rigorous genetic approaches to study human disease, development and cell biology where conventional animal models or tissue culture systems do not adequately recapitulate human biology. To do this we are  leveraging our expertise in human stem cell techniques and genome editing, humanized mouse models to elucidate processes of  human stem cells renewal and differentiation and during tumor formation.

Recent Publications

2021

Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations. Kramer DJ, Aisenberg EE, Kosillo P, Friedmann D, Stafford DA, Lee AY, Luo L, Hockemeyer D, Ngai J, Bateup HS. Cell Rep. 2021.

Cancer-associated POT1 mutations lead to telomere elongation without induction of a DNA damage response. Kim WT, Hennick K, Johnson J, Finnerty B, Choo S, Short SB, Drubin C, Forster R, McMaster ML, Hockemeyer D. The Embo Journal. 2021.

Recent News

Hockemeyer Halloween Party

10/2023

Hockemeyer Halloween Party

Hockemeyer Holiday Party

12/2022

Hockemeyer Holiday Party

2022 Bateup and Hockemeyer Lab Joint Annual BBQ

09/2022

2022 Bateup and Hockemeyer Lab Joint Annual BBQ

Shy passed his quals

04/2022

Congratulations to Shy for passing his qualifying exam!

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Parkinson’s Moving Day in San Francisco

04/2022

Parkinson’s Moving Day in San Francisco

The Hockemeyer lab and Rio lab joined the Parkinson’s Moving Day in San Francisco!

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Contact

Li Ka Shing Center

Positions

We are currently looking for motivated postdoctoral scholars. Interested applicants should submit CV and cover letter to:

Inside Li Ka Shing Center

Contact

Office phone: (510) 664-9851

Lab phone: (510) 664-4891

Lab e-mail address:

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